Lung Cancer: The Bad and the Worse
by Douglas Hanna
In terms of deaths caused by various forms of cancer, lung cancer ranks
second only to breast cancer. The National Cancer Institute recently reported
that an estimated 172,570 new cases of lung cancer will be reported this year
and that 163,510 American will die from this disease.
Lung cancer is caused predominantly by smoking. One expert says that in the
case of Small Cell Lung Carcinoma (cancer), it is almost always caused by
smoking.
Lung cancer is called lung cancer because it begins in the lungs. The right
lung has three sections, the left lung has two. Each section is called a lobe.
Sometimes the term "bronchogenic cancer" is used to refer to lung cancer as most
lung cancers begin in one of the two breathing tubes, the bronchi, in the
lungs.
There are two major types of lung cancer. One is the Small Cell Lung Cancer
(SCLC) mentioned in the previous paragraph. The other is Non-Small Cell Lung
Cancer (NSCLC).
Non-Small Cell Lung Cancer has three subtypes: Adenocarcinoma, Squamous Cell
Carcinoma and Large Cell Undifferentiated Carcinoma. NSCLC is the least
"serious" of the two types. In fact, if it is detected early, it is possible
that it can be cured with surgery.
Andenocarcinoma accounts for about 40 percent of lung cancer cases in the
U.S. It is the most common cancer among women and can be seen in non-smokers.
Squamous Cell Carcinoma represents about 30 to 35 percent of lung cancers and
tends to stay localized in the chest longer than other types of lung cancer.
Large Cell Undifferentiated Carcinoma represents only about five to 15 percent
of lung cancers in the U.S. The incidence of this type of cancer seems to be
decreasing.
The worst and most aggressive form of lung cancer is Small Cell Lung Cancer.
It represents only about 15 to 20 percent of all lung cancers. It spreads to the
lymph nodes and other organs more quickly than NSCLC, but seems more responsive
to chemotherapy drugs.
Non-Small Cell Lung Cancer is described in stages - Stage I through IV. WebMD
recently reports survival rates of NSCLC as:
· Stage 1A or 1B with no lymph node involvement has a five-year survival rate
of 43 to 64 percent when treated with surgery.
· Stage IIA or IIB with a single lymph node involvement, when treated with
surgery, has a five-year survival rate of 20 to 40 percent.
· Stage IIIA with a single lymph node involvement in the center of the chest,
when treated with surgery has a five-year survival rate of 15 to 25 percent.
· Stage IIIB with lymph node involvement in the chest and neck, when treated
with radiation without other treatment, has a five-year survival rate of five to
seven percent.
· Stage IIIB with lymph node involvement in the chest and neck, when treated
with radiation and chemotherapy, has a five-year survival rate between seven and
17 percent.
· Stage IV with extensive lymph node involvement or cancer that has spread to
other organs, hen treated with chemotherapy and palliative care to reduce
symptoms and increase comfort has a one-year survival rate.
The prognosis is much bleaker for patients with Small Cell Lung Cancer. This
form of cancer is found in two stages: limited or extensive. The limited version
is that which is found in only one lung and nearby lymph nodes. The extensive
type has spread outside the lung to other parts of the chest or body
(metastasized). Limited SCLC when treated with chemotherapy and radiation
therapy has an average survival time of 18 to 20 months. The extensive form of
SCLC when treated with chemotherapy has a survival time of 10 to 12 months.
Ttwo-year survival rate is one to three percent, and the five-year survival rate
less than two percent.
The majority of people diagnosed with SCLC will die despite the best
available treatment.
While surgery plays the most important part in the treatment of Non-Small
Cell Lung Cancer, chemotherapy is always the chosen treatment for Small Cell
Lung Cancer. In the case of limited stage SCLC, radiation therapy may also be
used as the cancer is still localized to the chest area where radiation can be
focused.
Small Cell Cancer Cells are so small they cannot be seen on scans. Even in
the case of limited stage SCLC, it is possible for some cells to break away from
the primary cancer and migrate to anywhere in the body. For this reason,
chemotherapy is the preferred treatment as it treats the whole body, unlike
radiation therapy which must be focused on a selected area. In act, chemotherapy
is the preferred treatment for both limited and extensive stage Small Cell Lung
Cancer.
Article by Douglas Hanna. Douglas is a retired advertising and marketing
executive and long-time Denver resident. He is the author of numerous articles
on family finances, Colorado vacations, and marketing.
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