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What is Bladder Cancer?

Bladder cancer is a disease in which malignant (cancer) cells form in the tissues of the bladder.

The bladder is a hollow organ in the lower part of the abdomen. It is shaped like a small balloon and has a muscular wall that allows it to get larger or smaller. The bladder stores urine until it is passed out of the body. Urine is the liquid waste that is made by the kidneys when they clean the blood. The urine passes from the two kidneys into the bladder through two tubes called ureters. When the bladder is emptied during urination, the urine goes from the bladder to the outside of the body through another tube called the urethra.

Bladder Cancer
Bladder Cancer Picture

There are three types of bladder cancer that begin in cells in the lining of the bladder. These cancers are named for the type of cells that become malignant (cancerous):

Transitional cell carcinoma: Cancer that begins in cells in the innermost tissue layer of the bladder. These cells are able to change shape depending on whether the bladder is full or empty and may be stretched without breaking apart. Most bladder cancers begin in the transitional cells.

Squamous cell carcinoma: Cancer that begins in squamous cells, which are thin, flat cells that may form in the bladder after long-term infection or irritation.

Adenocarcinoma: Cancer that begins in glandular (secretory) cells. Glandular cells in the lining of the bladder produce and release fluids such as mucus.

Cancer that is confined to the lining of the bladder is called superficial bladder cancer. Cancer that begins in the transitional cells may spread through the lining of the bladder and invade the muscle wall of the bladder or spread to nearby organs and lymph nodes; this is called invasive bladder cancer.

Smoking, gender, and diet can affect the risk of developing bladder cancer

Risk factors include the following:

  • Smoking.
  • Being exposed to certain substances at work, such as rubber, certain dyes and textiles, paint, and hairdressing supplies.
  • A diet high in fried meats and fat.
  • Being older, male, or white.
  • Having an infection caused by a certain parasite.
  • Possible signs of bladder cancer include blood in the urine or pain during urination.

These and other symptoms may be caused by bladder cancer:

Other conditions may cause the same symptoms. A doctor should be consulted if any of the following problems occur:

  • Blood in the urine (slightly rusty to bright red in color).
  • Frequent urination, or feeling the need to urinate without being able to do so.
  • Pain during urination.
  • Lower back pain.
  • Tests that examine the urine, vagina, or rectum are used to help detect (find) and diagnose bladder cancer.

National Cancer Institute

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